This one is a huge study of 408 males tracked from adolescence into their mid-30s and it found no difference between heavy early-onset smokers and low/non-users:
Findings from latent class growth curve analysis identified 4 distinct subgroups of marijuana users: early onset chronic users, late increasing users, adolescence-limited users, and low/nonusers. Results indicated that the 4 marijuana use trajectory groups were not significantly different in terms of their physical and mental health problems assessed in the mid-30s.Strangely enough, it doesn't seem to be getting much of a run in the media.
The War on Drugs is unjust nonsense.